ARG45075

anti-MYH7B antibody

anti-MYH7B antibody for ICC/IF,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes MYH7B
Tested Reactivity Hu, Ms, Rat
Tested Application ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name MYH7B
Antigen Species Mouse
Immunogen A synthetic peptide (coupled to KLH) corresponding to amino acid residues in the hinge region from mouse MYH7B/MHC14. This sequence is highly conserved in rat and human MYH7B, and has less than 50% identity with other MYH family members.
Conjugation Un-conjugated
Alternate Names MYH7B, Myosin Heavy Chain 7B, KIAA1512, LncMYH7b, MYH14, MHC14, Myosin, Heavy Polypeptide 7B, Cardiac Muscle, Beta, Antigen MLAA-21, Slow A MYH14, DJ756N5.1, Myosin-7B, Myosin Heavy Chain 7B, Cardiac Muscle Beta Isoform, Myosin, Heavy Chain 7B, Cardiac Muscle, Beta, Myosin Cardiac Muscle Beta Chain, U937-Associated Antigen

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:300
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Antigen Affinity Purified.
Buffer PBS, 0.05% NaN3, 50% Glycerol and 0.1 % BSA.
Stabilizer 50% Glycerol and 0.1 % BSA
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 57644 Human MYH7B

GeneID: 668940 Mouse MYH7B

Swiss-port # A2AQP0 Mouse Myosin-7B

Swiss-port # A7E2Y1 Human Myosin-7B

Gene Symbol MYH7B
Gene Full Name Myosin Heavy Chain 7B
Background The myosin II molecule is a multi-subunit complex consisting of two heavy chains and four light chains. This gene encodes a heavy chain of myosin II, which is a member of the motor-domain superfamily. The heavy chain includes a globular motor domain, which catalyzes ATP hydrolysis and interacts with actin, and a tail domain in which heptad repeat sequences promote dimerization by interacting to form a rod-like alpha-helical coiled coil. This heavy chain subunit is a slow-twitch myosin. Alternatively spliced transcript variants have been found, but the full-length nature of these variants is not determined. [provided by RefSeq, Mar 2010]
Function Involved in muscle contraction. [Uniprot]
Cellular Localization Membrane, Thick filament. [Uniprot]
Calculated MW 226 kDa