ARG65296

anti-MYO5A antibody

anti-MYO5A antibody for ICC/IF,Western blot and Human,Mouse

Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes MYO5A
Tested Reactivity Hu, Ms
Predict Reactivity Cow, Rat
Tested Application ICC/IF, WB
Specificity This antibody is expected to recognize both reported isoforms (NP_000250.3; NP_001135967.1).
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name MYO5A
Antigen Species Human
Immunogen C-ETKQLELDLN
Conjugation Un-conjugated
Alternate Names GS1; MYH12; Unconventional myosin-Va; MYR12; Myosin-12; MYO5; Dilute myosin heavy chain, non-muscle; Myoxin; Myosin heavy chain 12

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1 - 3 µg/ml
WB1 - 3 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by antigen affinity chromatography.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 17918 Mouse MYO5A

GeneID: 4644 Human MYO5A

Swiss-port # Q99104 Mouse Unconventional myosin-Va

Swiss-port # Q9Y4I1 Human Unconventional myosin-Va

Background This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined. [provided by RefSeq, Dec 2008]
Research Area Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody
Calculated MW 215 kDa