ARG44711
anti-MYO6 antibody
anti-MYO6 antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes MYO6 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, IP, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | MYO6 |
| Antigen Species | Human |
| Conjugation | Un-conjugated |
| Alternate Names | MYO6; Myosin VI; KIAA0389; Unconventional Myosin-VI; Unconventional Myosin-6; DFNA22; DFNB37; Deafness, Autosomal Recessive 37 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MYO6 |
| Gene Full Name | Myosin Vi |
| Background | This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| Function | Myosins are actin-based motor molecules with ATPase activity. |
| Cellular Localization | Cell membrane, Cell projection, Coated pit, #Cytoplasm, Cytoplasmic vesicle, Endosome, Golgi apparatus, Membrane, Nucleus |
| Calculated MW | 150 kDa |
| PTM | Phosphoprotein |
