ARG59007
anti-Methylmalonyl-CoA mutase antibody
anti-Methylmalonyl-CoA mutase antibody for ICC/IF,Western blot and Human,Mouse
Overview
Product Description | Rabbit Polyclonal antibody recognizes Methylmalonyl-CoA mutase |
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Tested Reactivity | Hu, Ms |
Tested Application | ICC/IF, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | Methylmalonyl-CoA mutase |
Antigen Species | Human |
Immunogen | KLH-conjugated synthetic peptide corresponding to aa. 492-526 of Human Methylmalonyl-CoA mutase. |
Conjugation | Un-conjugated |
Alternate Names | Methylmalonyl-CoA isomerase; MCM; EC 5.4.99.2; Methylmalonyl-CoA mutase, mitochondrial |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
Positive Control | K562 |
Properties
Form | Liquid |
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Purification | Purification with Protein A and immunogen peptide. |
Buffer | PBS and 0.09% (W/V) Sodium azide. |
Preservative | 0.09% (W/V) Sodium azide |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # P16332 Mouse Methylmalonyl-CoA mutase, mitochondrial Swiss-port # P22033 Human Methylmalonyl-CoA mutase, mitochondrial |
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Gene Symbol | MUT |
Gene Full Name | methylmalonyl CoA mutase |
Background | This gene encodes the mitochondrial enzyme methylmalonyl Coenzyme A mutase. In humans, the product of this gene is a vitamin B12-dependent enzyme which catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA, while in other species this enzyme may have different functions. Mutations in this gene may lead to various types of methylmalonic aciduria. [provided by RefSeq, Jul 2008] |
Function | Involved in the degradation of several amino acids, odd-chain fatty acids and cholesterol via propionyl-CoA to the tricarboxylic acid cycle. MCM has different functions in other species. [UniProt] |
Cellular Localization | Mitochondrion matrix. [UniProt] |
Calculated MW | 83 kDa |