ARG52341

anti-Mitochondria antibody [113-1]

anti-Mitochondria antibody [113-1] for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Controls and Markers antibody; Metabolism antibody; Signaling Transduction antibody

Overview

Product Description

Mouse Monoclonal antibody [113-1] recognizes Mitochondria

Tested Reactivity Hu
Species Does Not React With Ms, Rat
Tested Application FACS, ICC/IF, IHC-P, WB
Host Mouse
Clonality Monoclonal
Clone 113-1
Isotype IgG1
Target Name Mitochondria
Antigen Species Human
Immunogen Human cell homogenate
Conjugation Un-conjugated

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1:100
ICC/IF1:800
IHC-P1:800
WB1:1000
Application Note Specific for human mitochondria in all cell types. The antibody works on acetone fixed and 2% paraformaldehyde fixed cells. The antibody also works for immunohistochemistry on 2% paraformaldehyde fixed (5-10 minutes) cryostat sections.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Total IgG fraction
Buffer Total IgG fraction
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Background Mitochondria are most commonly known as the power plants of the cell as they produce ATP, but they are also involved in many other important cellular processes such as cell signaling, growth and differentiation (McBride et al., 2006). In addition, mitochondria have been shown to play a role in apoptosis (Green 1998). This antibody is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells, including neurons and embryonic stem cells.
Research Area Controls and Markers antibody; Metabolism antibody; Signaling Transduction antibody

Clone References

Overexpression of the cell adhesion molecule claudin-9 is associated with invasion in pituitary oncocytomas.

Hong L et al.
Hum Pathol.,  (2014)

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Identification of a subtype-specific ENC1 gene related to invasiveness in human pituitary null cell adenoma and oncocytomas.

Feng J et al.
J Neurooncol.,  (2014)

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A tissue-engineered humanized xenograft model of human breast cancer metastasis to bone.

IHC-P / Human

Thibaudeau L et al.
Dis Model Mech.,  (2014)

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Characterization of mesenchymal stem cells from human normal and hyperplastic gingiva.

IHC-P / Human

Tang L et al.
J Cell Physiol.,  (2011)

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