ARG63727

anti-MyD88 antibody

anti-MyD88 antibody for ELISA,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Cell Biology and Cellular Response antibody; Immune System antibody; Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes MyD88
Tested Reactivity Hu
Predict Reactivity Ms, Rat, Dog
Tested Application ELISA, IHC-P, WB
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name MyD88
Antigen Species Human
Immunogen C-IKYKAMKKEFP
Conjugation Un-conjugated
Alternate Names MYD88D; Myeloid differentiation primary response protein MyD88

Application Instructions

Application Suggestion
Tested Application Dilution
ELISA5 - 10 µg/ml (detection Ab)
IHC-P4 - 6 µg/ml
WB0.1 - 0.3 µg/ml
Application Note IHC-P: Antigen Retrieval: Steam tissue section in Tris/EDTA buffer (pH 9.0).
WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by antigen affinity chromatography.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 4615 Human MYD88

Swiss-port # Q99836 Human Myeloid differentiation primary response protein MyD88

Background This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Highlight Related products:
MYD88 antibodies; Anti-Goat IgG secondary antibodies;
Related poster download:
Toll-like Receptor.pdf
Research Area Cell Biology and Cellular Response antibody; Immune System antibody; Signaling Transduction antibody
Calculated MW 33 kDa