ARG58208
anti-NAT1 antibody
anti-NAT1 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes NAT1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NAT1 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to aa. 172-201 of Human NAT1. (NEEFLHSDLLEDSKYRKIYSFTLKPRTIED) |
| Conjugation | Un-conjugated |
| Alternate Names | NAT-1; N-acetyltransferase type 1; Arylamine N-acetyltransferase 1; EC 2.3.1.5; Monomorphic arylamine N-acetyltransferase; NATI; Arylamide acetylase 1; AAC1; MNAT |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | NAT1 |
| Gene Full Name | N-acetyltransferase 1 (arylamine N-acetyltransferase) |
| Background | This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] |
| Function | Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens. [UniProt] |
| Cellular Localization | Cytoplasm. [UniProt] |
| Calculated MW | 34 kDa |
