ARG58208

anti-NAT1 antibody

anti-NAT1 antibody for Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes NAT1
Tested Reactivity Hu
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name NAT1
Antigen Species Human
Immunogen Synthetic peptide corresponding to aa. 172-201 of Human NAT1. (NEEFLHSDLLEDSKYRKIYSFTLKPRTIED)
Conjugation Un-conjugated
Alternate Names NAT-1; N-acetyltransferase type 1; Arylamine N-acetyltransferase 1; EC 2.3.1.5; Monomorphic arylamine N-acetyltransferase; NATI; Arylamide acetylase 1; AAC1; MNAT

Application Instructions

Application Suggestion
Tested Application Dilution
WB0.1 - 0.5 µg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA.
Preservative 0.05% Sodium azide
Stabilizer 5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 9 Human NAT1

Swiss-port # P18440 Human Arylamine N-acetyltransferase 1

Gene Symbol NAT1
Gene Full Name N-acetyltransferase 1 (arylamine N-acetyltransferase)
Background This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Function Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens. [UniProt]
Cellular Localization Cytoplasm. [UniProt]
Calculated MW 34 kDa