ARG43934
anti-NDST4 antibody
anti-NDST4 antibody for ELISA,Flow cytometry,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes NDST4 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, FACS, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NDST4 |
| Antigen Species | Human |
| Immunogen | Human NDST4 recombinant protein |
| Expression System | E.coli |
| Conjugation | Un-conjugated |
| Protein Full Name | Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 |
| Alternate Names | NDST4; N-Deacetylase And N-Sulfotransferase 4; Bifunctional Heparan Sulfate N-Deacetylase/N-Sulfotransferase 4; N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 4; Glucosaminyl N-Deacetylase/N-Sulfotransferase 4; N-Heparan Sulfate Sulfotransferase 4; N-HSST 4; NDST-4; N-Deacetylase/N-Sulfotransferase 4; EC 2.8.2.8; N-HSST; NHSST4; HSST4 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified with Immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9H3R1 Human Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 |
|---|---|
| Gene Symbol | NDST4 |
| Gene Full Name | N-Deacetylase And N-Sulfotransferase 4 |
| Background | Predicted to enable [heparan sulfate]-glucosamine N-sulfotransferase activity and deacetylase activity. Predicted to be involved in heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus. |
| Function | Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has low deacetylase activity but high sulfotransferase activity. |
| Cellular Localization | Golgi apparatus, Membrane |
| Calculated MW | 101 kDa |
| PTM | Disulfide bond, Glycoprotein |
