ARG65563
anti-NDUFA13 antibody
anti-NDUFA13 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody; Gene Regulation antibody; Metabolism antibody
Overview
Product Description | Rabbit Polyclonal antibody recognizes NDUFA13 |
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Tested Reactivity | Hu, Ms |
Tested Application | IHC-P, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | NDUFA13 |
Antigen Species | Human |
Immunogen | Fusion protein of human NDUFA13 |
Conjugation | Un-conjugated |
Alternate Names | CI-B16.6; NADH-ubiquinone oxidoreductase B16.6 subunit; CGI-39; Gene associated with retinoic and interferon-induced mortality 19 protein; Cell death regulatory protein GRIM-19; Complex I-B16.6; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13; GRIM19; CDA016; B16.6; GRIM-19; Gene associated with retinoic and IFN-induced mortality 19 protein |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
Positive Control | Mouse spleen and skeletal muscle tissue, Human hepatocellular carcinoma, Mouse liver and Human placenta tissue, HeLa and 293T cell tissue. |
Properties
Form | Liquid |
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Purification | Purified by antigen-affinity chromatography. |
Buffer | 1XPBS (pH 7.4), 0.05% Sodium azide and 40% Glycerol |
Preservative | 0.05% Sodium azide |
Stabilizer | 40% Glycerol |
Concentration | 2 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # Q9ERS2 Mouse NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 Swiss-port # Q9P0J0 Human NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 |
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Gene Symbol | NDUFA13 |
Gene Full Name | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 |
Background | This gene encodes a subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain. The protein is required for complex I assembly and electron transfer activity. The protein binds the signal transducers and activators of transcription 3 (STAT3) transcription factor, and can function as a tumor suppressor. The human protein purified from mitochondria migrates at approximately 16 kDa. Transcripts originating from an upstream promoter and capable of expressing a protein with a longer N-terminus have been found, but their biological validity has not been determined. |
Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in CARD15-mediated innate mucosal responses and serve to regulate intestinal epithelial cell responses to microbes. [UniProt] |
Highlight | Related products: Anti-Rabbit IgG secondary antibodies; Related poster download: The Structure & Functions of Mitochondria.pdf |
Research Area | Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody; Gene Regulation antibody; Metabolism antibody |
Calculated MW | 17 kDa |