ARG44060
anti-NFKBIZ antibody
anti-NFKBIZ antibody for Flow cytometry,ICC/IF,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal recognizes NFKBIZ |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NFKBIZ |
| Antigen Species | Human |
| Immunogen | Human NFKBIZ recombinant protein (Position: Q247-H577). |
| Conjugation | Un-conjugated |
| Alternate Names | NFKBIZ; NFKB Inhibitor Zeta; MAIL; INAP; IL-1 Inducible Nuclear Ankyrin-Repeat Protein; NF-Kappa-B Inhibitor Zeta; Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells Inhibitor, Zeta; Molecule Possessing Ankyrin Repeats Induced By Lipopolysaccharide; I-Kappa-B-Zeta; IkappaBzeta; FLJ34463; IkB-Zeta; IKBZ; IkappaB-Zeta |
Application Instructions
| Application Suggestion |
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| Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | NFKBIZ |
| Gene Full Name | NFKB Inhibitor Zeta |
| Background | This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene. |
| Function | Involved in the induction of T helper 17 cells (Th17) differentiation upon recognition of antigen by T cell antigen receptor (TCR). |
| Cellular Localization | Nucleus |
| Calculated MW | 78 kDa |
