ARG22198
anti-NHE3 antibody
anti-NHE3 antibody for ICC/IF,Western blot and Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes NHE3 |
|---|---|
| Tested Reactivity | Ms, Rat |
| Tested Application | ICC/IF, WB |
| Specificity | Detects ~84kDa. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Target Name | NHE3 |
| Antigen Species | Rat |
| Immunogen | Synthetic peptide around aa. 809 to 831 of Rat NHE3 |
| Conjugation | Un-conjugated |
| Alternate Names | Sodium/hydrogen exchanger 3; Na; +; Solute carrier family 9 member 3; NHE-3; NHE3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS, 0.09% Sodium azide and 50% Glycerol |
| Preservative | 0.09% Sodium azide |
| Stabilizer | 50% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | Slc9a3 |
| Gene Full Name | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 |
| Function | Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. [UniProt] |
| Cellular Localization | Membrane |
| Calculated MW | 93 kDa |
| PTM | Phosphorylated by PKA, which inhibits activity. Phosphorylation at Ser-663 by SGK1 is associated with increased abundance at the cell membrane. |
