ARG22070
anti-NKG2A + C + E antibody [20d5] (PE)
anti-NKG2A + C + E antibody [20d5] (PE) for Blocking,Flow cytometry and Mouse
Overview
Product Description | PE-conjugated Rat Monoclonal antibody [20d5] recognizes NKG2A + C + E |
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Tested Reactivity | Ms |
Tested Application | BL, FACS |
Specificity | Mouse NKG2-A + C + E |
Host | Rat |
Clonality | Monoclonal |
Clone | 20d5 |
Isotype | IgG2a, kappa |
Target Name | NKG2A + C + E |
Antigen Species | Mouse |
Immunogen | CHO cells transfected with B6 allele of NKG2A gene |
Conjugation | PE |
Alternate Names | NK cell receptor A; CD159 antigen-like family member A; NKG2-A/NKG2-B type II integral membrane protein; CD159A; CD antigen CD159a; NKG2; NKG2A; NKG2-A/B-activating NK receptor |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Buffer | PBS, 0.1% Sodium azide and Sucrose. |
Preservative | 0.1% Sodium azide |
Stabilizer | Sucrose |
Concentration | 0.1 mg/ml |
Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Gene Symbol | KLRC1 |
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Gene Full Name | killer cell lectin-like receptor subfamily C, member 1 |
Background | Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jan 2015] |
Function | Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. [UniProt] |
Calculated MW | 26 kDa |