ARG44358
anti-NLRP5 antibody
anti-NLRP5 antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes NLRP5 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NLRP5 |
| Antigen Species | Human |
| Immunogen | Human NLRP5 recombinant fusion protein (a.a. sequence: 157-256). |
| Conjugation | Un-conjugated |
| Alternate Names | NLRP5; NLR Family Pyrin Domain Containing 5; MATER; Maternal Antigen That Embryos Require; CLR19.8; PYPAF8; PAN11; NALP5; Nucleotide-Binding Oligomerization Domain, Leucine Rich Repeat And Pyrin Domain Containing 5; NACHT, Leucine Rich Repeat And PYD Containing 5; NACHT, LRR And PYD Domains-Containing Protein 5; Mater Protein Homolog; OZEMA19 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS, 0.02% sodium azide and 50% Glycerol. |
| Preservative | 0.02% sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P59047 Human NACHT, LRR and PYD domains-containing protein 5 Swiss-port # Q9R1M5 Mouse NACHT, LRR and PYD domains-containing protein 5 |
|---|---|
| Gene Symbol | NLRP5 |
| Gene Full Name | NLR Family Pyrin Domain Containing 5 |
| Background | The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). Expression of this gene is restricted to the oocyte. A mouse gene that encodes a maternal oocyte protein, similar to this encoded protein, is required for normal early embryogenesis. |
| Function | As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions via regulation of actin dynamics. |
| Cellular Localization | Cytoplasm, Cytoplasmic vesicle, Golgi apparatus, Mitochondrion, Nucleus |
| Calculated MW | 134 kDa |
