ARG40542
anti-NOMO1 + NOMO2 + NOMO3 antibody
anti-NOMO1 + NOMO2 + NOMO3 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes NOMO1 + NOMO2 + NOMO3 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NOMO1 + NOMO2 + NOMO3 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 873-1222 of Human NOMO2 (NP_001004060.1). |
| Conjugation | Un-conjugated |
| Alternate Names | Nodal modulator 2; PM5; pM5 protein 2; Nomo |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | BxPC-3 | ||||
| Observed Size | ~ 140 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | NOMO2 |
| Gene Full Name | NODAL modulator 2 |
| Background | This gene encodes a protein originally thought to be related to the collagenase gene family. This gene is one of three highly similar genes in a region of duplication located on the p arm of chromosome 16. These three genes encode closely related proteins that may have the same function. The protein encoded by one of these genes has been identified as part of a protein complex that participates in the Nodal signaling pathway during vertebrate development. Mutations in ABCC6, which is located nearby, rather than mutations in this gene are associated with pseudoxanthoma elasticum (PXE). Two transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
| Function | May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning, via its interaction with NCLN. [UniProt] |
| Cellular Localization | Endoplasmic reticulum membrane; Single-pass membrane protein. [UniProt] |
| Calculated MW | 139 kDa |
