ARG64477

anti-NOVA1 antibody

anti-NOVA1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Neuroscience antibody

Overview

Product Description Goat Polyclonal antibody recognizes NOVA1
Tested Reactivity Hu
Tested Application IHC-P, WB
Specificity This antibody is expected to recognise all three reported isoforms (NP_002506.2 ; NP_006480.2 ; NP_006482.1)
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name NOVA1
Antigen Species Human
Immunogen C-REMPQNVAKTEPVS
Conjugation Un-conjugated
Alternate Names Paraneoplastic Ri antigen; Neuro-oncological ventral antigen 1; Nova-1; Onconeural ventral antigen 1; RNA-binding protein Nova-1; Ventral neuron-specific protein 1

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P5 µg/ml
WB0.01 - 0.03 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by antigen affinity chromatography.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 4857 Human NOVA1

Swiss-port # P51513 Human RNA-binding protein Nova-1

Background This gene encodes a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Research Area Neuroscience antibody
Calculated MW 52 kDa