ARG23715
anti-NPAS4 antibody [S408-79]
anti-NPAS4 antibody [S408-79] for Western blot and Human,Mouse,Rat
Overview
| Product Description | Mouse Monoclonal antibody [S408-79] recognizes NPAS4 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | S408-79 |
| Isotype | IgG1 |
| Target Name | NPAS4 |
| Antigen Species | Rat |
| Immunogen | Fusion protein amino acids 597-802 (C-terminus) of Rat NPAS4. |
| Conjugation | Un-conjugated |
| Alternate Names | PASD10; Neuronal PAS domain-containing protein 4; Class E basic helix-loop-helix protein 79; PAS domain-containing protein 10; HLH-PAS transcription factor NXF; NXF; Le-PAS; bHLHe79; Neuronal PAS4 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Observed Size | ~ 90 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein G. |
| Buffer | PBS (pH 7.4), 0.1% Sodium azide and 50% Glycerol. |
| Preservative | 0.1% Sodium azide |
| Stabilizer | 50% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | NPAS4 |
| Gene Full Name | neuronal PAS domain protein 4 |
| Background | NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2; MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004 [PubMed 14701734]).[supplied by OMIM, Mar 2008] |
| Function | Acts as a transcriptional activator in the presence of ARNT. Can activate the CME (CNS midline enhancer) element and the expression of the drebrin gene. [UniProt] |
| Cellular Localization | Nucleus [UniProt] |
| Calculated MW | 87 kDa |
| PTM | Ubiquitinated, leading to degradation by the proteosome. [UniProt] |
