ARG42221

anti-NPTX1 / NP1 antibody

anti-NPTX1 / NP1 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes NPTX1 / NP1
Tested Reactivity Hu, Ms, Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name NPTX1 / NP1
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide between aa. 322-350 of Human NPTX1 / NP1.
Conjugation Un-conjugated
Alternate Names Neuronal pentraxin-1; NP-I; NP1; Neuronal pentraxin I

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:25
WB1:1000
Application Note IHC-P: Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Human brain
Observed Size ~ 50 kDa

Properties

Form Liquid
Purification Purification with Protein A and immunogen peptide.
Buffer PBS and 0.09% (W/V) Sodium azide.
Preservative 0.09% (W/V) Sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 18164 Mouse NPTX1

GeneID: 266777 Rat NPTX1

GeneID: 4884 Human NPTX1

Gene Symbol NPTX1
Gene Full Name neuronal pentraxin I
Background NPTX1 is a member of the neuronal pentraxin gene family. Neuronal pentraxin 1 is similar to the rat NP1 gene which encodes a binding protein for the snake venom toxin taipoxin. Human NPTX1 mRNA is exclusively localized to the nervous system. [provided by RefSeq, Jul 2008]
Function May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses. [UniProt]
Cellular Localization Cytoplasmic vesicle, secretory vesicle. [UniProt]
Calculated MW 47 kDa