ARG42218

anti-NPTX2 antibody

anti-NPTX2 antibody for Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes NPTX2
Tested Reactivity Hu
Predict Reactivity Ms, Rat
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name NPTX2
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 90-240 of Human NPTX2 (NP_002514.1).
Conjugation Un-conjugated
Alternate Names Neuronal pentraxin II; Neuronal pentraxin-2; NP-II; NARP; NP2

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control BxPC-3
Observed Size ~ 47 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 4885 Human NPTX2

Swiss-port # P47972 Human Neuronal pentraxin-2

Gene Symbol NPTX2
Gene Full Name neuronal pentraxin II
Background This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq, Feb 2009]
Function Likely to play role in the modification of cellular properties that underlie long-term plasticity. Binds to agar matrix in a calcium-dependent manner (By similarity). [UniProt]
Cellular Localization Secreted. [UniProt]
Calculated MW 47 kDa