ARG40906
anti-NQO2 antibody
anti-NQO2 antibody for Flow cytometry,Western blot and Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes NQO2 |
|---|---|
| Tested Reactivity | Ms, Rat |
| Tested Application | FACS, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NQO2 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide derived from Human NQO2. |
| Conjugation | Un-conjugated |
| Alternate Names | NRH dehydrogenase [quinone] 2; NMOR2; DHQV; Quinone reductase 2; NRH:quinone oxidoreductase 2; QR2; Ribosyldihydronicotinamide dehydrogenase [quinone]; DIA6; EC 1.10.5.1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | Mouse heart |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q6AY80 Rat Ribosyldihydronicotinamide dehydrogenase [quinone] Swiss-port # Q9JI75 Mouse Ribosyldihydronicotinamide dehydrogenase [quinone] |
|---|---|
| Gene Symbol | NQO2 |
| Gene Full Name | NAD(P)H dehydrogenase, quinone 2 |
| Background | This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] |
| Function | The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. [UniProt] |
| Cellular Localization | Cytoplasm. [UniProt] |
| Calculated MW | 26 kDa |
