ARG58759
anti-NR5A2 antibody
anti-NR5A2 antibody for Western blot and Human,Pig
Overview
| Product Description | Goat Polyclonal antibody recognizes NR5A2 |
|---|---|
| Tested Reactivity | Hu, Pig |
| Predict Reactivity | Ms, Rat, Cow, Dog |
| Tested Application | WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NR5A2 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide from the internal region of Human NR5A2 (NP_995582.1; NP_003813.1). (C-TDYDRSPFVTSPIS) |
| Conjugation | Un-conjugated |
| Alternate Names | NR5A2; Nuclear Receptor Subfamily 5 Group A Member 2; LRH-1; FTZ-F1beta; FTZ-F1; HB1F-2; HB1F; B1F2; LRH1; FTF; CYP7A Promoter-Binding Factor; B1F; CPF; B1-Binding Factor, Hepatocyte Transcription Factor Which Activates Enhancer II Of Hepatitis B Virus; Nuclear Receptor Subfamily 5, Group A, Member 2; Fetoprotein-Alpha 1 (AFP) Transcription Factor; Alpha-1-Fetoprotein Transcription Factor; Hepatocytic Transcription Factor HB1F-3; Hepatocytic Transcription Factor; Liver Receptor Homolog-1; Liver Receptor Homolog 1; B1-Binding Factor |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| Observed Size | ~ 55 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O00482 Human Nuclear receptor subfamily 5 group A member 2 |
|---|---|
| Gene Symbol | NR5A2 |
| Gene Full Name | nuclear receptor subfamily 5, group A, member 2 |
| Background | The protein encoded by this gene is a DNA-binding zinc finger transcription factor and is a member of the fushi tarazu factor-1 subfamily of orphan nuclear receptors. The encoded protein is involved in the expression of genes for hepatitis B virus and cholesterol biosynthesis, and may be an important regulator of embryonic development. |
| Function | Nuclear receptor that acts as a key metabolic sensor by regulating the expression of genes involved in bile acid synthesis, cholesterol homeostasis and triglyceride synthesis. Together with the oxysterol receptors NR1H3/LXR-alpha and NR1H2/LXR-beta, acts as an essential transcriptional regulator of lipid metabolism. Plays an anti-inflammatory role during the hepatic acute phase response by acting as a corepressor: inhibits the hepatic acute phase response by preventing dissociation of the N-Cor corepressor complex. |
| Cellular Localization | Nucleus |
| Calculated MW | 61 kDa |
| PTM | Isopeptide bond, Ubl conjugation |
