ARG44120
anti-NT5C antibody
anti-NT5C antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal recognizes NT5C |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NT5C |
| Antigen Species | Human |
| Immunogen | Human NT5C recombinant protein (Position: H35-R179). |
| Conjugation | Un-conjugated |
| Alternate Names | NT5C; 5', 3'-Nucleotidase, Cytosolic; DNT-1; DNT1; UMPH2; PN-I; CdN; 5' Nucleotidase, Deoxy (Pyrimidine), Cytosolic Type C 2; 5'(3')-Deoxyribonucleotidase, Cytosolic Type; Uridine 5-Prime Monophosphate Hydrolase 2; Cytosolic 5',3'-Pyrimidine Nucleotidase; Deoxy-5'-Nucleotidase 1; Uridine 5'-Monophosphate Phosphohydrolase 2; Epididymis Secretory Sperm Binding Protein; Epididymis Luminal Protein 74; EC 3.1.3.-; HEL74; PN-II; P5N2; DNT |
Application Instructions
| Application Suggestion |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8TCD5 Human 5'(3')-deoxyribonucleotidase, cytosolic type |
|---|---|
| Gene Symbol | NT5C |
| Gene Full Name | 5', 3'-Nucleotidase, Cytosolic |
| Background | This gene encodes a nucleotidase that catalyzes the dephosphorylation of the 5' deoxyribonucleotides (dNTP) and 2'(3')-dNTP and ribonucleotides, but not 5' ribonucleotides. Of the different forms of nucleotidases characterized, this enzyme is unique in its preference for 5'-dNTP. It may be one of the enzymes involved in regulating the size of dNTP pools in cells. Alternatively spliced transcript variants have been found for this gene. |
| Function | Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP. |
| Cellular Localization | Cytoplasm |
| Calculated MW | 23 kDa |
| PTM | Phosphoprotein |
