ARG66942
anti-NUT / NUTM1 antibody [SQab22272]
anti-NUT / NUTM1 antibody [SQab22272] for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Recombinant Rabbit Monoclonal antibody [SQab22272] recognizes NUT / NUTM1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | SQab22272 |
| Isotype | IgG |
| Target Name | NUT / NUTM1 |
| Antigen Species | Human |
| Immunogen | A synthetic peptide corresponding to the sequence of Human NUT / NUTM1. |
| Conjugation | Un-conjugated |
| Protein Full Name | NUT family member 1 |
| Alternate Names | NUT; FAM22H; C15orf55; Nuclear protein in testis; NUT family member 1 |
Application Instructions
| Application Suggestion |
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| Application Note | IHC-P: Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0). Incubate the samples at RT (18-25°C) for 51 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| Positive Control | Human testis tissue |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 40% Glycerol and 0.05%BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | NUTM1 |
| Gene Full Name | NUT midline carcinoma family member 1 |
| Background | Predicted to be located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022] |
| Function | Plays a role in the regulation of proliferation. Regulates TERT expression by modulating SP1 binding to TERT promoter binding sites. [provide by uniprot] |
| Cellular Localization | Cytoplasm, Nucleus |
| Calculated MW | 120.3 kDa |
| PTM | Methylation, Phosphoprotein; Methylated at Gln-1046 by N6AMT1.1 Phosphorylation on Ser-1026, Ser-1029 or Ser-1031 is important for cytoplasmic export. |
