ARG64263

anti-Neurexin 1 antibody

anti-Neurexin 1 antibody for Flow cytometry,Western blot and Human

Neuroscience antibody; Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes Neurexin 1
Tested Reactivity Hu
Predict Reactivity Ms, Rat, Dog
Tested Application FACS, WB
Specificity This antibody is expected to recognise both reported isoforms (NP_004792.1 and NP_620072.1).
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name Neurexin 1
Antigen Species Human
Immunogen C-KEKQPSSAKSSNKN
Conjugation Un-conjugated
Alternate Names Neurexin-1; PTHSL2; Neurexin-1-alpha; Neurexin I-alpha; SCZD17; Hs.22998

Application Instructions

Application Suggestion
Tested Application Dilution
FACS10 µg/ml
WB0.5 - 1 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 9378 Human NRXN1

Swiss-port # Q9ULB1 Human Neurexin-1

Background Neurexins function in the vertebrate nervous system as cell adhesion molecules and receptors. Two neurexin genes are among the largest known in human (NRXN1 and NRXN3). By using alternate promoters, splice sites and exons, predictions of hundreds or even thousands of distinct mRNAs have been made. Most transcripts use the upstream promoter and encode alpha-neurexin isoforms; fewer transcripts are produced from the downstream promoter and encode beta-neurexin isoforms. Alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and they interact with neurexophilins. Beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. The RefSeq Project has decided to create only a few representative transcript variants of the multitude that are possible. [provided by RefSeq, Oct 2008]
Research Area Neuroscience antibody; Signaling Transduction antibody
Calculated MW 162 kDa
PTM Highly O-glycosylated and minor N-glycosylated.