ARG40541
anti-Neurotensin / Neuromedin-N Precursor antibody
anti-Neurotensin / Neuromedin-N Precursor antibody for IHC-Formalin-fixed paraffin-embedded sections and Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Neurotensin / Neuromedin-N Precursor |
|---|---|
| Tested Reactivity | Ms, Rat |
| Tested Application | IHC-P |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Neurotensin / Neuromedin-N Precursor |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 24-148 of Human Neurotensin / Neuromedin-N Precursor (NP_006174.1). |
| Conjugation | Un-conjugated |
| Alternate Names | NMN-125; NN; NTS1; Neurotensin/neuromedin N; NT/N; NmN; NT; NmN-125 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | NTS |
| Gene Full Name | neurotensin |
| Background | This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Neurotensin also exhibits antimicrobial activity against bacteria and fungi. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active. [provided by RefSeq, Oct 2014] |
| Function | Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle. [UniProt] |
| Cellular Localization | Secreted. Cytoplasmic vesicle, secretory vesicle. Note=Packaged within secretory vesicles. [UniProt] |
| Calculated MW | 20 kDa |
