ARG54130
anti-Noggin antibody
anti-Noggin antibody for ICC/IF,Western blot and Human
Controls and Markers antibody; Developmental Biology antibody; Signaling Transduction antibody
Overview
| Product Description | Mouse Monoclonal antibody recognizes NOG |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ICC/IF, WB |
| Specificity | ARG54130 Noggin antibody [1D2-G8-G1] recognize overexpressing Noggin protein by WB and ICC/IF analysis. |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG3 |
| Target Name | Noggin |
| Antigen Species | Human |
| Immunogen | Purified recombinant human Noggin protein fragments expressed in E.coli. |
| Conjugation | Un-conjugated |
| Alternate Names | SYM1; Noggin; SYNS1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 26 kDa |
Properties
| Form | Liquid |
|---|---|
| Buffer | Ascites |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | NOG |
| Gene Full Name | noggin |
| Background | Essential for cartilage morphogenesis and joint formation.Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. |
| Function | Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. Essential for cartilage morphogenesis and joint formation. Inhibits chondrocyte differentiation through its interaction with GDF5 (PubMed:21976273). [UniProt] |
| Cellular Localization | Secreted. |
| Research Area | Controls and Markers antibody; Developmental Biology antibody; Signaling Transduction antibody |
| Calculated MW | 26 kDa |
