ARG40598

anti-Norepinephrine Transporter antibody

anti-Norepinephrine Transporter antibody for Western blot and Human,Mouse

Overview

Product Description Rabbit Polyclonal antibody recognizes Norepinephrine Transporter
Tested Reactivity Hu, Ms
Predict Reactivity Rat
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name Norepinephrine Transporter
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 1-70 of Human Norepinephrine Transporter (NP_001165975.1).
Conjugation Un-conjugated
Alternate Names SLC6A5; Solute carrier family 6 member 2; NAT1; Norepinephrine transporter; NET; Sodium-dependent noradrenaline transporter; NET1

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Mouse spinal cord
Observed Size 68 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 20538 Mouse SLC6A2

GeneID: 6530 Human SLC6A2

Swiss-port # O55192 Mouse Sodium-dependent noradrenaline transporter

Swiss-port # P23975 Human Sodium-dependent noradrenaline transporter

Gene Symbol SLC6A2
Gene Full Name solute carrier family 6 (neurotransmitter transporter), member 2
Background This gene encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
Function Amine transporter. Terminates the action of noradrenaline by its high affinity sodium-dependent reuptake into presynaptic terminals. [UniProt]
Cellular Localization Membrane, Multi-pass membrane protein. [UniProt]
Calculated MW 69 kDa