ARG11072
anti-Norepinephrine Transporter antibody [NET-05]
anti-Norepinephrine Transporter antibody [NET-05] for Western blot and Mouse,Rat
Overview
Product Description | Mouse Monoclonal antibody [NET-05] recognizes Norepinephrine Transporter |
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Tested Reactivity | Ms, Rat |
Species Does Not React With | Hu |
Tested Application | WB |
Specificity | This antibody recognizes Mouse and Rat NET. It does not recognize Human NET. |
Host | Mouse |
Clonality | Monoclonal |
Clone | NET-05 |
Isotype | IGg2b |
Target Name | Norepinephrine Transporter |
Antigen Species | Mouse |
Immunogen | KLH-conjugated synthetic peptide around the N-terminal region of Mouse Norepinephrine Transporter. |
Conjugation | Un-conjugated |
Alternate Names | SLC6A5; Solute carrier family 6 member 2; NAT1; Norepinephrine transporter; NET; Sodium-dependent noradrenaline transporter; NET1 |
Application Instructions
Predict Reactivity Note | Sequence homology: Cow (92%); Cat, Human and non-human primate (85%) | ||||
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Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | This antibody is prepared by Ammonium Sulfate precipitation from hybridoma culture media followed by dialysis against PBS. |
Buffer | PBS and 50% Glycerol. |
Stabilizer | 50% Glycerol |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # O55192 Mouse Sodium-dependent noradrenaline transporter |
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Gene Symbol | SLC6A2 |
Gene Full Name | solute carrier family 6 (neurotransmitter transporter), member 2 |
Background | This gene encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010] |
Function | Amine transporter. Terminates the action of noradrenaline by its high affinity sodium-dependent reuptake into presynaptic terminals. [UniProt] |
Cellular Localization | Cell membrane; Multi-pass membrane protein. [UniProt] |
Calculated MW | 69 kDa |