ARG64804

anti-ORAI1 / CRACM1 antibody

anti-ORAI1 / CRACM1 antibody for Western blot and Human

Immune System antibody; Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes ORAI1 / CRACM1
Tested Reactivity Hu
Predict Reactivity Dog, Pig
Tested Application WB
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name ORAI1 / CRACM1
Antigen Species Human
Immunogen C-KKQPGQPRPTSKP
Conjugation Un-conjugated
Alternate Names Protein orai-1; CRACM1; Transmembrane protein 142A; IMD9; ORAT1; Calcium release-activated calcium channel protein 1; TAM2; TMEM142A

Application Instructions

Application Suggestion
Tested Application Dilution
WB0.03 - 0.1 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by antigen affinity chromatography.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 84876 Human ORAI1

Swiss-port # Q96D31 Human Calcium release-activated calcium channel protein 1

Background The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1). [provided by RefSeq, Sep 2011]
Research Area Immune System antibody; Signaling Transduction antibody
Calculated MW 33 kDa
PTM N-glycosylated.
Ubiquitinated.
Cys-195 is oxidated, leading to inactivate channel activity.