ARG43970
anti-ORP10 / OSBPL10 antibody
anti-ORP10 / OSBPL10 antibody for ELISA,Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ORP10 / OSBPL10 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ELISA, FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ORP10 / OSBPL10 |
| Antigen Species | Human |
| Immunogen | Human ORP10 / OSBPL10 recombinant protein |
| Expression System | E.coli |
| Conjugation | Un-conjugated |
| Protein Full Name | Oxysterol-binding protein-related protein 10 |
| Alternate Names | OSBPL10; Oxysterol Binding Protein Like 10; Oxysterol-Binding Protein-Related Protein 10; OSBP-Related Protein 10; ORP-10; ORP10; OSBP9; Oxysterol Binding Protein-Like 10 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified with Immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9BXB5 Human Oxysterol-binding protein-related protein 10 |
|---|---|
| Gene Symbol | OSBPL10 |
| Gene Full Name | Oxysterol Binding Protein Like 10 |
| Background | This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Function | Probable lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane. Its ability to bind phosphatidylserine, suggests that it specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P (PubMed:23934110) (Probable). Plays a role in negative regulation of lipid biosynthesis. |
| Cellular Localization | Cytoplasm, Cytoskeleton |
| Calculated MW | 84 kDa |
| PTM | Methylation, Phosphoprotein |
