ARG41200
anti-OSBPL2 / ORP2 antibody
anti-OSBPL2 / ORP2 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes OSBPL2 / ORP2 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | OSBPL2 / ORP2 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 291-480 of Human OSBPL2 / ORP2 (NP_653081.1). |
| Conjugation | Un-conjugated |
| Alternate Names | Oxysterol-binding protein-related protein 2; ORP-2; DNFA67; ORP2; OSBP-related protein 2; DFNA67 |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | HeLa | ||||
| Observed Size | 56 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9H1P3 Human Oxysterol-binding protein-related protein 2 |
|---|---|
| Gene Symbol | OSBPL2 |
| Gene Full Name | oxysterol binding protein-like 2 |
| Background | This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2014] |
| Function | Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate. Binds 25-hydroxycholesterol. [UniProt] |
| Calculated MW | 55 kDa |
