ARG59963

anti-OSGEP antibody

anti-OSGEP antibody for Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes OSGEP
Tested Reactivity Hu, Ms, Rat
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name OSGEP
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 1-335 of Human OSGEP (NP_060277.1).
Conjugation Un-conjugated
Alternate Names EC 2.3.1.234; PRSMG1; OSGEP1; hOSGEP; tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP; Probable tRNA N6-adenosine threonylcarbamoyltransferase; N6-L-threonylcarbamoyladenine synthase; t; 6; KAE1; O-sialoglycoprotein endopeptidase; GCPL1

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Rat liver, Mouse ovary and HL60
Observed Size 36 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 290028 Rat OSGEP

GeneID: 55644 Human OSGEP

GeneID: 66246 Mouse OSGEP

Gene Symbol OSGEP
Gene Full Name O-sialoglycoprotein endopeptidase
Function Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. [UniProt]
Cellular Localization Cytoplasm. Nucleus. [UniProt]
Calculated MW 36 kDa