ARG44449
anti-PADI3 / PAD3 antibody
anti-PADI3 / PAD3 antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PADI3 / PAD3 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PADI3 / PAD3 |
| Antigen Species | Human |
| Immunogen | Human PADI3 / PAD3 recombinant protein |
| Conjugation | Un-conjugated |
| Alternate Names | PADI3; Peptidyl Arginine Deiminase 3; PDI3; Peptidyl Arginine Deiminase, Type III; Protein-Arginine Deiminase Type III; Protein-Arginine Deiminase Type-3; Peptidylarginine Deiminase III; EC 3.5.3.15; PAD3; UHS1 |
Application Instructions
| Application Suggestion |
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| Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified with Immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PADI3 |
| Gene Full Name | Peptidyl Arginine Deiminase 3 |
| Background | This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. This gene exists in a cluster with four other paralogous genes. |
| Function | Catalyzes the deimination of arginine residues of proteins. |
| Cellular Localization | Cytoplasm |
| Calculated MW | 75 kDa |
