ARG63692
anti-PADI4 / PAD4 antibody
anti-PADI4 / PAD4 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections and Human
Gene Regulation antibody; Metabolism antibody; Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes PADI4 / PAD4 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ICC/IF, IHC-P |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PADI4 / PAD4 |
| Antigen Species | Human |
| Immunogen | AQGTLIRVTPEQPC |
| Conjugation | Un-conjugated |
| Alternate Names | PADI4; Peptidyl Arginine Deiminase 4; PDI5; PADI5; PDI4; PAD; Peptidyl Arginine Deiminase, Type IV; Peptidyl Arginine Deiminase, Type V; Protein-Arginine Deiminase Type IV; Protein-Arginine Deiminase Type-4; EC 3.5.3.15; HL-60 PAD; PAD4; Peptidylarginine Deiminase IV; PADI-H Protein |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by antigen affinity chromatography. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PADI4 |
| Gene Full Name | Peptidyl Arginine Deiminase 4 |
| Background | This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. [provided by RefSeq, Jul 2008] |
| Function | Catalyzes the citrullination/deimination of arginine residues of proteins such as histones, thereby playing a key role in histone code and regulation of stem cell maintenance. [UniProt] |
| Cellular Localization | Cytoplasm, Nucleus. [UniProt] |
| Research Area | Gene Regulation antibody; Metabolism antibody; Signaling Transduction antibody |
| Calculated MW | 74 kDa |
| PTM | Citrullination. [UniProt] |
