ARG55281
anti-PARC antibody
anti-PARC antibody for Western blot,ICC/IF and Human,Mouse
Cancer antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PARC |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PARC |
| Antigen Species | Human |
| Immunogen | Synthetic peptide (17 aa) within the last 50 aa of Human PARC. |
| Conjugation | Un-conjugated |
| Alternate Names | p53-associated parkin-like cytoplasmic protein; PARC; H7AP1; CUL-9; UbcH7-associated protein 1; Cullin-9 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | Daudi Cell Lysate |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS and 0.02% Sodium azide |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CUL9 |
| Gene Full Name | cullin 9 |
| Function | Core component of a Cul9-RING ubiquitin-protein ligase complex, a complex that mediates ubiquitination and subsequent degradation of BIRC5 and is required to maintain microtubule dynamics and genome integrity. Acts downstream of the 3M complex, which inhibits CUL9 activity, leading to prevent ubiquitination of BIRC5. Cytoplasmic anchor protein in p53/TP53-associated protein complex. Regulates the subcellular localization of p53/TP53 and subsequent function. [UniProt] |
| Research Area | Cancer antibody |
| Calculated MW | 281 kDa |
| PTM | In vitro, self-ubiquitination in the presence of E1, E2 and ubiquitin. Neddylated. |
