ARG64279

anti-PCBP4 antibody

anti-PCBP4 antibody for Western blot and Human

Cell Biology and Cellular Response antibody; Cell Death antibody; Gene Regulation antibody

Overview

Product Description Goat Polyclonal antibody recognizes PCBP4
Tested Reactivity Hu
Predict Reactivity Ms, Rat, Dog
Tested Application WB
Specificity This antibody is expected to recognise all reported isoforms (NP_065151.1, NP_127501.1, NP_127502.1 and NP_127503.1).
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name PCBP4
Antigen Species Human
Immunogen C-NGSKKAERQKFSPY
Conjugation Un-conjugated
Alternate Names Alpha-CP4; Poly; CBP; LIP4; rC; MCG10

Application Instructions

Application Suggestion
Tested Application Dilution
WB1 - 3 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by antigen affinity chromatography.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 57060 Human PCBP4

Swiss-port # P57723 Human Poly(rC)-binding protein 4

Background This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined. [provided by RefSeq, Jul 2008]
Research Area Cell Biology and Cellular Response antibody; Cell Death antibody; Gene Regulation antibody
Calculated MW 41 kDa