ARG57038
anti-PDCL3 antibody [8F9]
anti-PDCL3 antibody [8F9] for ICC/IF,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [8F9] recognizes PDCL3 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ICC/IF, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 8F9 |
| Isotype | IgG1, kappa |
| Target Name | PDCL3 |
| Antigen Species | Human |
| Immunogen | Recombinant fragment around aa. 1-239 of Human PDCL3. |
| Conjugation | Un-conjugated |
| Alternate Names | VIAF; HTPHLP; VIAF1; VIAF-1; PHLP3; PHLP2A; Viral IAP-associated factor 1; PhPL3; Phosducin-like protein 3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 10% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PDCL3 |
| Gene Full Name | phosducin-like 3 |
| Background | This gene encodes a member of the phosducin-like protein family and is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin. Members of the phosducin-like protein family have been shown to bind to the beta-gamma subunits of G proteins. [provided by RefSeq, Jul 2008] |
| Function | Acts as a chaperone for the angiogenic VEGF receptor KDR/VEGFR2, controlling its abundance and inhibiting its ubiquitination and degradation. Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination. [UniProt] |
| Calculated MW | 28 kDa |
