ARG10793
anti-PDE1C antibody
anti-PDE1C antibody for Confocal microscopy (Confocal),ELISA,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot,Dot blot and Human,Mouse,Rat
Overview
Product Description | Rabbit Polyclonal antibody recognizes PDE1C |
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Tested Reactivity | Hu, Ms, Rat |
Tested Application | Confocal, Dot, ELISA, ICC/IF, IHC-P, IP, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | PDE1C |
Antigen Species | Human |
Immunogen | Synthetic peptide from Human PDE1C. |
Conjugation | Un-conjugated |
Alternate Names | Hcam3; cam-PDE 1C; EC 3.1.4.17; Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C; Cam-PDE 1C; hCam-3 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Affinity purified. |
Buffer | Tris-Glycine Buffer (pH 7.4 - 7.8), Hepes, 0.02% Sodium azide, 30% Glycerol and 0.5% BSA. |
Preservative | 0.02% Sodium azide |
Stabilizer | 30% Glycerol and 0.5% BSA |
Concentration | 0.5 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | PDE1C |
Gene Full Name | phosphodiesterase 1C, calmodulin-dependent 70kDa |
Background | Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]).[supplied by OMIM, Oct 2009] |
Function | Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a high affinity for both cAMP and cGMP. [UniProt] |
Calculated MW | PDE1C1: 76 kDa PDE1C2: 70 kDa |