ARG41188
anti-PDE4DIP antibody
anti-PDE4DIP antibody for Western blot and Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PDE4DIP |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PDE4DIP |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 1-310 of Human PDE4DIP (NP_071754.3). |
| Conjugation | Un-conjugated |
| Alternate Names | MMGL; Phosphodiesterase 4D-interacting protein; CMYA2; Myomegalin; Cardiomyopathy-associated protein 2 |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Mouse skeletal muscle | ||||
| Observed Size | ~ 250 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PDE4DIP |
| Gene Full Name | phosphodiesterase 4D interacting protein |
| Background | The protein encoded by this gene serves to anchor phosphodiesterase 4D to the Golgi/centrosome region of the cell. Defects in this gene may be a cause of myeloproliferative disorder (MBD) associated with eosinophilia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010] |
| Function | May function as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes. [UniProt] |
| Cellular Localization | Golgi apparatus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Isoform 13: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton. Golgi apparatus. Note=Associated with the microtubule network at the growing distal tip of microtubules (PubMed:29162697). Targeting to the Golgi apparatus requires AKAP9 (PubMed:25217626). [UniProt] |
| Calculated MW | 265 kDa |
