ARG10808
anti-PDE7B antibody
anti-PDE7B antibody for Confocal microscopy (Confocal),ELISA,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot,Dot blot and Human
Overview
Product Description | Rabbit Polyclonal antibody recognizes PDE7B |
---|---|
Tested Reactivity | Hu |
Tested Application | Confocal, Dot, ELISA, ICC/IF, IHC-P, IP, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | PDE7B |
Antigen Species | Human |
Immunogen | Synthetic cyclic peptide common to all PDE7B variants. |
Conjugation | Un-conjugated |
Alternate Names | cAMP-specific 3',5'-cyclic phosphodiesterase 7B; bA472E5.1; EC 3.1.4.53 |
Application Instructions
Application Suggestion |
|
||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
---|---|
Purification | Affinity purified. |
Buffer | Tris-Glycine Buffer (pH 7.4 - 7.8), Hepes, 0.02% Sodium azide, 30% Glycerol and 0.5% BSA. |
Preservative | 0.02% Sodium azide |
Stabilizer | 30% Glycerol and 0.5% BSA |
Concentration | 0.5 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # Q9NP56 Human cAMP-specific 3',5'-cyclic phosphodiesterase 7B |
---|---|
Gene Symbol | PDE7B |
Gene Full Name | phosphodiesterase 7B |
Background | The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.[provided by RefSeq, Apr 2009] |
Function | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain. [UniProt] |
Calculated MW | 52 kDa |