ARG22292
anti-PDI antibody
anti-PDI antibody for Western blot,Immunohistochemistry,ICC/IF,Immunoprecipitation and Dog,Human,Monkey,Mouse,Rat,Xenopus laevis,Bovine,Guinea pig,Hamster,Pig,Sheep
Overview
Product Description | Rabbit Polyclonal antibody recognizes PDI |
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Tested Reactivity | Hu, Ms, Rat, Bov, Dog, Gpig, Hm, Mk, Pig, Sheep, Xenopus laevis |
Tested Application | ICC/IF, IHC, IP, WB |
Specificity | Detects ~58kDa. |
Host | Rabbit |
Clonality | Polyclonal |
Target Name | PDI |
Antigen Species | Rat |
Immunogen | KLH-conjugated synthetic peptide from Rat PDI |
Conjugation | Un-conjugated |
Alternate Names | PDA2; Pancreas-specific protein disulfide isomerase; PDIR; PDIP; PDI; Protein disulfide-isomerase A2; PDIp; EC 5.3.4.1 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Affinity purification with immunogen. |
Buffer | PBS (pH 7.4), 0.09% Sodium azide and 50% Glycerol |
Preservative | 0.09% Sodium azide |
Stabilizer | 50% Glycerol |
Concentration | 1 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | Pdia2 |
Gene Full Name | protein disulfide isomerase family A, member 2 |
Background | Protein disulfide isomerases (EC 5.3.4.1), such as PDIP, are endoplasmic reticulum (ER) resident proteins that catalyze protein folding and thiol-disulfide interchange reactions (Desilva et al., 1996 [PubMed 8561901]).[supplied by OMIM, Mar 2008] |
Function | Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins. [UniProt] |
Cellular Localization | Endoplasmic Reticulum, Endoplasmic reticulum lumen |
Calculated MW | 58 kDa |
PTM | The disulfide-linked homodimer exhibits an enhanced chaperone activity. Glycosylated. |