ARG65748
anti-PDI antibody
anti-PDI antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
2
Overview
Product Description | Rabbit Polyclonal antibody recognizes PDI |
---|---|
Tested Reactivity | Hu, Ms |
Tested Application | ICC/IF, IHC-P, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | PDI |
Antigen Species | Human |
Immunogen | KLH-conjugated synthetic peptide corresponding to a region of Human PDI (NP_006840.2). |
Conjugation | Un-conjugated |
Alternate Names | PDA2; Pancreas-specific protein disulfide isomerase; PDIR; PDIP; PDI; Protein disulfide-isomerase A2; PDIp; EC 5.3.4.1 |
Application Instructions
Application Suggestion |
|
||||||||
---|---|---|---|---|---|---|---|---|---|
Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
Positive Control | HeLa, MCF-7, PANC, HepG2, HUVEC, NIH/3T3, L929, F9, Jurkat, A431, A549, Mouse liver tissue, Mouse kidney tissue, Mouse brain tissue, Human lung carcinoma tissue, Human kidney, Human brain, Human liver, Human colon carcinoma tissue |
Properties
Form | Liquid |
---|---|
Purification | Affinity purification with immunogen. |
Buffer | TBS (pH 7.4), 0.05% Sodium azide, 40% Glycerol and 1% BSA. |
Preservative | 0.05% Sodium azide |
Stabilizer | 40% Glycerol and 1% BSA |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
---|---|
Gene Symbol | PDIA2 |
Gene Full Name | protein disulfide isomerase family A, member 2 |
Background | Protein disulfide isomerases (EC 5.3.4.1), such as PDIP, are endoplasmic reticulum (ER) resident proteins that catalyze protein folding and thiol-disulfide interchange reactions (Desilva et al., 1996 [PubMed 8561901]). [supplied by OMIM, Mar 2008] |
Function | Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins. [UniProt] |
Calculated MW | 58 kDa |
PTM | The disulfide-linked homodimer exhibits an enhanced chaperone activity. Glycosylated. |
Customer's Feedback