ARG43888
anti-PDS5B antibody
anti-PDS5B antibody for ELISA,Flow cytometry,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PDS5B |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | ELISA, FACS, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PDS5B |
| Antigen Species | Human |
| Immunogen | Human PDS5B recombinant protein |
| Expression System | E.coli |
| Conjugation | Un-conjugated |
| Protein Full Name | Sister chromatid cohesion protein PDS5 homolog B |
| Alternate Names | PDS5B; PDS5 Cohesin Associated Factor B; AS3; Androgen-Induced Proliferation Inhibitor; KIAA0979; CG008; APRIN |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified with Immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q4VA53 Mouse Sister chromatid cohesion protein PDS5 homolog B Swiss-port # Q9NTI5 Human Sister chromatid cohesion protein PDS5 homolog B |
|---|---|
| Gene Symbol | PDS5B |
| Gene Full Name | PDS5 Cohesin Associated Factor B |
| Background | This gene encodes a protein that interacts with the conserved protein complex termed cohesin. The cohesin complex holds together sister chromatids and facilitates accurate chromosome segregation during mitosis and meiosis. This protein is also a negative regulator of cell proliferation and may be a tumor-suppressor gene. |
| Function | Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Plays a role in androgen-induced proliferative arrest in prostate cells. |
| Cellular Localization | Nucleus |
| Calculated MW | 165 kDa |
| PTM | Acetylation, Phosphoprotein |
