ARG42753

anti-PEX11B antibody

anti-PEX11B antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes PEX11B
Tested Reactivity Hu, Ms, Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name PEX11B
Antigen Species Human
Immunogen Synthetic peptide corresponding to aa. 132-177 of Human PEX11B.
Conjugation Un-conjugated
Alternate Names Protein PEX11 homolog beta; Peroxisomal biogenesis factor 11B; Peroxin-11B; Peroxisomal membrane protein 11B; PEX14B; PEX11-BETA; PEX11-beta

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:50 - 1:200
WB1:500 - 1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control MCF7, Raw264.7 and PC12
Observed Size ~ 28 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Purity > 95% (by SDS-PAGE)
Buffer PBS (pH 7.2), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 18632 Mouse PEX11B

GeneID: 8799 Human PEX11B

Swiss-port # O96011 Human Peroxisomal membrane protein 11B

Swiss-port # Q9Z210 Mouse Peroxisomal membrane protein 11B

Gene Symbol PEX11B
Gene Full Name peroxisomal biogenesis factor 11 beta
Background The protein encoded by this gene facilitates peroxisomal proliferation and interacts with PEX19. The encoded protein is found in the peroxisomal membrane. Several transcript variants, some protein-coding and some not protein-coding, have been found for this gene. [provided by RefSeq, Dec 2012]
Function Involved in peroxisomal proliferation (PubMed:9792670). May regulate peroxisome division by recruiting the dynamin-related GTPase DNM1L to the peroxisomal membrane (PubMed:12618434). Promotes membrane protrusion and elongation on the peroxisomal surface (PubMed:20826455). [UniProt]
Cellular Localization Peroxisome membrane; Single-pass membrane protein. [UniProt]
Calculated MW 28 kDa