ARG40805

anti-PEX14 antibody

anti-PEX14 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse

Overview

Product Description Rabbit Polyclonal antibody recognizes PEX14
Tested Reactivity Hu, Ms
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name PEX14
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 118-377 of Human PEX14 (NP_004556.1).
Conjugation Un-conjugated
Alternate Names NAPP2; dJ734G22.2; Peroxin-14; Peroxisomal membrane anchor protein PEX14; PTS1 receptor-docking protein; PBD13A; Peroxisomal membrane protein PEX14; Pex14p

Application Instructions

Predict Reactivity Note Mouse
Application Suggestion
Tested Application Dilution
IHC-P1:50 - 1:200
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 5195 Human PEX14

GeneID: 56273 Mouse PEX14

Swiss-port # O75381 Human Peroxisomal membrane protein PEX14

Swiss-port # Q9R0A0 Mouse Peroxisomal membrane protein PEX14

Gene Symbol PEX14
Gene Full Name peroxisomal biogenesis factor 14
Background This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome. [provided by RefSeq, Jul 2008]
Function Peroxisome membrane protein that is an essential component of the peroxisomal import machinery. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PEX5). Plays a key role for peroxisome movement through a direct interaction with tubulin. [UniProt]
Cellular Localization Peroxisome membrane; Peripheral membrane protein; Cytoplasmic side. [UniProt]
Calculated MW 41 kDa