ARG40810
anti-PEX6 antibody
anti-PEX6 antibody for Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PEX6 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PEX6 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 741-980 of Human PEX6 (NP_000278.3). |
| Conjugation | Un-conjugated |
| Alternate Names | PAF-2; PBD4A; Peroxisomal biogenesis factor 6; Peroxisomal-type ATPase 1; PAF2; PXAAA1; PDB4B; Peroxisome assembly factor 2; Peroxin-6 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | BT-474 | ||||
| Observed Size | 105 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PEX6 |
| Gene Full Name | peroxisomal biogenesis factor 6 |
| Background | This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) family of ATPases. This member is a predominantly cytoplasmic protein, which plays a direct role in peroxisomal protein import and is required for PTS1 (peroxisomal targeting signal 1, a C-terminal tripeptide of the sequence ser-lys-leu) receptor activity. Mutations in this gene cause peroxisome biogenesis disorders of complementation group 4 and complementation group 6. [provided by RefSeq, Oct 2008] |
| Function | Involved in peroxisome biosynthesis. Required for stability of the PTS1 receptor. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes. [UniProt] |
| Cellular Localization | Cytoplasm. Peroxisome membrane. Cell projection, cilium, photoreceptor outer segment. Note=Associated with peroxisomal membranes. Localized at the base of the outer segment of photoreceptor cells (PubMed:26593283). [UniProt] |
| Calculated MW | 104 kDa |
Images (1) Click the Picture to Zoom In
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ARG40810 anti-PEX6 antibody WB image
Western blot: 25 µg of BT-474 cell lysate stained with ARG40810 anti-PEX6 antibody at 1:1000 dilution.
