ARG66418

anti-PGA5 antibody [SQab18120]

anti-PGA5 antibody [SQab18120] for Western blot,ELISA,ICC/IF,Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Pig

Overview

Product Description Mouse Monoclonal antibody [SQab18120] recognizes PGA5
Tested Reactivity Hu, Ms, Pig
Tested Application ELISA, FACS, ICC/IF, IHC-P, WB
Host Mouse
Clonality Monoclonal
Clone SQab18120
Isotype IgG1, kappa
Target Name PGA5
Antigen Species Human
Immunogen Recombinant Human PGA5 protein.
Conjugation Un-conjugated
Alternate Names EC 3.4.23.1; Pepsin A-5; Pg5; Pepsinogen-5

Application Instructions

Application Suggestion
Tested Application Dilution
ELISA1:3000 - 1:10000
FACS1:400 - 1:1000
ICC/IF1:400 - 1:1000
IHC-PAssay-dependent
WB1:2500 - 1:5000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Purification Affinity purification with immunogen.
Buffer PBS (pH 7.4) and 0.01% Thimerosal.
Preservative 0.01% Thimerosal
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 5222 Human PGA5

Swiss-port # P0DJD9 Human Pepsin A-5

Gene Symbol PGA5
Gene Full Name pepsinogen 5, group I (pepsinogen A)
Background This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer. [provided by RefSeq, Jul 2015]
Function Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. [UniProt]
Cellular Localization Secreted. [UniProt]
Calculated MW 42 kDa