ARG57065
anti-PGM1 antibody [84G2]
anti-PGM1 antibody [84G2] for Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [84G2] recognizes PGM1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 84G2 |
| Isotype | IgG1, kappa |
| Target Name | PGM1 |
| Antigen Species | Human |
| Immunogen | Recombinant fragment around aa. 1-562 of Human PGM1. |
| Conjugation | Un-conjugated |
| Alternate Names | CDG1T; Phosphoglucomutase-1; GSD14; EC 5.4.2.2; Glucose phosphomutase 1; PGM 1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 10% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PGM1 |
| Gene Full Name | phosphoglucomutase 1 |
| Background | The protein encoded by this gene is an isozyme of phosphoglucomutase (PGM) and belongs to the phosphohexose mutase family. There are several PGM isozymes, which are encoded by different genes and catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, this PGM isozyme is predominant, representing about 90% of total PGM activity. In red cells, PGM2 is a major isozyme. This gene is highly polymorphic. Mutations in this gene cause glycogen storage disease type 14. Alternativley spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Mar 2010] |
| Function | This enzyme participates in both the breakdown and synthesis of glucose. [UniProt] |
| Calculated MW | 61 kDa |
| PTM | Phosphorylation at Thr-467 by PAK1 significantly enhances enzymatic activity. |
