ARG44575
anti-PHF17 / JADE1 antibody
anti-PHF17 / JADE1 antibody for Flow cytometry,ICC/IF,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PHF17 / JADE1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PHF17 / JADE1 |
| Antigen Species | Human |
| Immunogen | Human PHF17 / JADE1 recombinant protein (aa. sequence: I93-D811). |
| Conjugation | Un-conjugated |
| Alternate Names | JADE1; Jade Family PHD Finger 1; PHD Finger Protein 17; PHF17; Jade Family PHD Finger Protein 1; Protein Jade-1; JADE-1; Gene For Apoptosis And Differentiation In Epithelia; PHD Protein Jade-1; KIAA1807 |
Application Instructions
| Application Suggestion |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Preservative | 4% Trehalose |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | JADE1 |
| Gene Full Name | Jade Family PHD Finger 1 |
| Background | Enables transcription coactivator activity. Involved in histone acetylation and negative regulation of canonical Wnt signaling pathway. Acts upstream of or within negative regulation of G1/S transition of mitotic cell cycle. Located in several cellular components, including ciliary basal body; cytosol; and nuclear speck. Part of histone acetyltransferase complex. [provided by Alliance of Genome Resources, Apr 2022] |
| Function | Negatively regulates canonical Wnt signaling; at least in part, cooperates with NPHP4 in this function. [Uniprot] |
| Cellular Localization | Cell projection, Chromosome, Cytoplasm, Cytoskeleton, Nucleus. [Uniprot] |
| Calculated MW | 96 kDa |
| PTM | Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation. [Uniprot] |
