ARG44383
anti-PI4 kinase beta / PI4KB antibody
anti-PI4 kinase beta / PI4KB antibody for ICC/IF,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes PI4 kinase beta / PI4KB |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | PI4 kinase beta / PI4KB |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 560-801 of human PI4KB |
| Conjugation | Un-conjugated |
| Alternate Names | PI4KB; Phosphatidylinositol 4-Kinase Beta; PI4K-BETA; Pi4K92; PIK4CB; Phosphatidylinositol 4-Kinase, Catalytic, Beta; PtdIns 4-Kinase Beta; EC 2.7.1.67; PI4KIII; NPIK; Phosphatidylinositol 4-Kinase, Wortmannin-Sensitive; Type III Phosphatidylinositol 4-Kinase Beta; PI4KIIIBETA; PI4K-Beta |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.01% Thimerosal and 50% Glycerol. |
| Preservative | 0.01% Thimerosal |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8BKC8 Mouse Phosphatidylinositol 4-kinase beta Swiss-port # Q9UBF8 Human Phosphatidylinositol 4-kinase beta |
|---|---|
| Gene Symbol | PI4KB |
| Gene Full Name | Phosphatidylinositol 4-Kinase Beta |
| Background | Enables 1-phosphatidylinositol 4-kinase activity and 14-3-3 protein binding activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process and phosphatidylinositol-mediated signaling. Located in Golgi membrane. |
| Function | Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking. |
| Cellular Localization | Cytoplasm, Endoplasmic reticulum, Golgi apparatus, Membrane, Mitochondrion, Mitochondrion outer membrane |
| Calculated MW | 91 kDa |
| PTM | Acetylation, Phosphoprotein |
