ARG57004

anti-PIG3 antibody [1C9]

anti-PIG3 antibody [1C9] for ICC/IF,Western blot and Human

Overview

Product Description Mouse Monoclonal antibody [1C9] recognizes PIG3
Tested Reactivity Hu
Tested Application ICC/IF, WB
Host Mouse
Clonality Monoclonal
Clone 1C9
Isotype IgG2a, kappa
Target Name PIG3
Antigen Species Human
Immunogen Recombinant fragment around aa. 1-332 of Human PIG3.
Conjugation Un-conjugated
Alternate Names Quinone oxidoreductase PIG3; EC 1.-.-.-; Tumor protein p53-inducible protein 3; PIG3; p53-induced gene 3 protein

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IFAssay-dependent
WB1:3000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purification with Protein G.
Buffer PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 10% Glycerol
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 9540 Human TP53I3

Swiss-port # Q53FA7 Human Quinone oxidoreductase PIG3

Gene Symbol TP53I3
Gene Full Name tumor protein p53 inducible protein 3
Background The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
Function May be involved in the generation of reactive oxygen species (ROS). Has low NADPH-dependent beta-naphthoquinone reductase activity, with a preference for 1,2-beta-naphthoquinone over 1,4-beta-naphthoquinone. Has low NADPH-dependent diamine reductase activity (in vitro). [UniProt]
Calculated MW 36 kDa